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MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF

MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF

Walter RF, Mairinger FD, Ting S, Vollbrecht C3 Mairinger T, Theegarten D, Christoph DC, Schmid KW, Wohlschlaeger J.: MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53. Br J Cancer. 2015 Feb 10. doi: 10.1038/bjc.2015.27